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It may also cause priapism, an erection lasting longer than 4 hours, damaging the penile tissue. An urgent medical evaluation is needed to prevent long-term damage if this occurs. Consumers should not use products that match one or more of the descriptions above.

Tell your doctor if you are pregnant or plan to become pregnant. You should not take tadalafil if you are allergic to it, or if you take other medicines to treat pulmonary arterial hypertension, such as riociguat (Adempas). Cialis 20mg should only be taken once a day, as this is the maximum daily dose of the medication for ED. Only take it more regularly or at a higher dose if instructed to do so by a medical professional.

This compares for example to sildenafil (Viagra) which lasts for around 4 hours. Erectile dysfunction can be caused by stress, psychosexual problems, and lifestyle choices such as smoking, heavy drinking, obesity, and lack of exercise. Other causes may include spinal injury or operations on the prostate or bowel. Regular cycling for 3 or more hours a day may also contribute to ED. Other oral PDE5 treatments include Viagra (sildenafil), Levitra (vardenafil), and Spedra (avanafil) which typically last 4 hours. A very rare but serious side effect is priapism - a continuous painful erection over a period of hours.

Avoid concomitant use of calcineurin inhibitors with PAXLOVID when close monitoring of immunosuppressant concentrations is not feasible. If co-administered, dose adjustment of the immunosuppressant and close and regular monitoring for immunosuppressant concentrations and adverse reactions are recommended during and after treatment with PAXLOVID. Obtain expert consultation to appropriately manage the complexity of this coadministration [see Warnings and Precautions (5.1)].

Tadalafil has moderate interactions with at least 152different drugs. Use&nbsp